Marissa Brash
Loma Linda University School of Public Health , USA
Title: Vegetarian Dietary Patterns and Self-Reported Lupus: A Cross-Sectional Analysis from the Adventist Health Study-2
Biography
Biography: Marissa Brash
Abstract
Purpose: To assess the association between a diagnosis of Systemic Lupus Erythematosus (SLE) and diet as well as demographic factors among subjects in the Adventist Health Study-2 (AHS-2) cohort. Methods: Unconditional logistic regression modeling was used to assess the association between self-reported SLE and vegetarian dietary status adjusted for age, ethnicity, body mass index (BMI), education, and smoking history among 74,907 AHS-2 participants. Results: Compared to non-Hispanic Whites, non-Hispanic Blacks were significantly more likely to report a diagnosis of SLE (OR 1.75, 95% CI 1.32, 2.32). A significantly higher proportion of 40-59 year olds (OR 1.85, 95% CI 1.16, 2.96) and those 60 or older (OR 1.68, 95% CI 1.03, 2.76) reported a diagnosis of SLE when compared to subjects younger than 40 years Those who reported having ever smoked were more likely to report SLE than those who had never smoked (OR 1.60, 95% CI 1.17, 2.18). Compared to non-vegetarians, the vegetarians had lower odds ratio of reporting SLE (OR=0.78, 95% CI 0.57, 1.07) with intermediate levels for the pesco-vegetarians who eat fish as the only source of meat, (OR 0.91, 95% CI 0.58, 1.42). (p(trend) < 0.05). Conclusion: Following a vegetarian, plant-based diet may be associated with lower risk of SLE.