Riadh Allani
Cardiovascular Diseases Epidemiology and Prevention Laboratory , Tunisia
Title: Immediate Complications of acute coronary syndrome: a Tunisian prospective multicenter study about 1178 patients
Biography
Biography: Riadh Allani
Abstract
Detailed knowledge of acute coronary syndrome (ACS) complications and their risk factors can help clinicians in making an early diagnosis. The aim of this paper was to analyze evolutionary and prognosis characteristics of this syndrome based on diagnostic classes. Tunisian Epidemiological Study on ACS "TEPS-ACS 2009-2010" was the data source of our research. It was a prospective multicenter inpatient study including 1178 patients admitted for ACS in cardiology units in Tunis District centers during the period from July 2009 to June 2010. Data was analyzed using Version 11.5 SPSS software. Results were expressed as percentage for categorical variables. Proportions' comparisons were made by chi-square test and those averages by Student t test and ANOVA. ACS patients were predominantly male (sex ratio = 2.57), with an age mean of 61 ± 12 years. They were distributed into three diagnostic classes, ST+ (48.8%), ST-TR+ (33.3%) and ST-TR- (17.9%). ST+ class was more frequent in less than 45 year old, men (53%) and current smoking (49.2%). Short-term complications were observed in 24.7% of patients with significantly higher frequency in ST+ (34.2%, p <0.001). They were dominated by heart failure (42.7%), hemodynamic complications (32.2%), conduction disorders (26.6%), necrosis recurrences (26.4%) and arrhythmias (22.5%) but no any significant difference between classes. Short-term mortality (first five days) was 3.9% and significantly higher for ST+ (6.6% against 1.6% and 1% in ST-TR+ and TR-ST-, p <0.001). Early diagnosis and appropriate management improve the prognosis of this disease which remains a leading cause of death in Tunisia.